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Abstract Precise manipulation of nanomaterials has shown great potential in facilitating the fabrication of functional hydrogel nanocomposites in applications such as soft robotics, biomedicine, structural health monitoring, and wearable sensing. Surface acoustic wave (SAW)-based acoustofluidics offers a contactless approach for nanoparticle manipulation. Meanwhile, digital light processing (DLP) has been extensively utilized in the hydrogel printing process due to its high-resolution fabrication capabilities. This study presents an innovative SAW acoustofluidics-assisted DLP system, enabling the patterning of nanoparticles embedded in matrix materials while facilitating programmed light exposure for the controllable photopolymerization of customized hydrogel nanocomposites. Instead of utilizing the acoustic potential field generated by SAWs, we leverage the accompanying electric field due to the piezoelectric effect of the lithium niobate (LiNbO3) substrate to generate electric field, enabling the electric field-driven patterning of multi-walled carbon nanotubes (MWCNTs) Laser Doppler vibrometry confirms the SAW-generated acoustic intensity fields. The analytical simulation together with the scanned data predicted the co-current electric field predicted the distribution of MWCNTs. By applying a programmed light pattern, we successfully fabricated hydrogel nanocomposites in the shape of a VT logo and produced hydrogel nanocomposite sensors. The capabilities of printed hydrogel nanocomposite sensors were demonstrated through beam vibration sensing, proving its potential application in structural health monitoring. The fabricated sensors demonstrated the capability to track finger movements, indicating their potential for wearable sensing applications. In summary, this study offers a unique approach for nanocomposites fabricating multi-material integration and material anisotropy control, thereby facilitating advanced smart material development. Future work will focus on exploring the fabrication of hydrogels containing other types of nanomaterials to enhance material conductivity and achieve other functions, aiming with the goal of developing nanocomposite sensors for applications in soft robotics, biomedicine, structural health monitoring, and wearable sensing. 

Abstract Cell patterning techniques play a pivotal role in the development of three-dimensional (3D) engineered tissues, holding significant promise in regenerative medicine, drug screening, and disease research. Current techniques encompass various mechanisms, such as nanoscale topographic patterning, mechanical loading, chemical coating, 3D inkjet printing, electromagnetic fields, and acoustic waves. In this study, we introduce a unique standing bulk waves-based acoustic cell patterning device designed for constructing anisotropic-engineered glioma tissues containing acoustically patterned human glioblastoma cell U251. Our device features two orthogonal pairs of piezoelectric transducers securely mounted on a customized holder. The energy of standing bulk waves generated from these transducers can be transmitted into the medium in a Petri dish through its bottom wall. Cells in the medium can be directed to the local minima of Gor’kov potential fields and trapped by the resultant acoustic radiation force. Through proof-of-concept experiments, we validate the functionality of our acoustic patterning device and assess the morphology and differentiation of U251 cells within the engineered glioma tissues. Our findings reveal that cells can be arranged in different distributions, such as parallel-line-like and lattice-like patterns. Moreover, the aligned cells exhibit more obvious elongation along the cell alignment orientation compared to the result of a control group. We anticipate that this study will catalyze the advancement in contactless cell patterning technologies within tissue engineering, facilitating the development of engineered tissues for applications in regenerative medicine and disease research. 

Abstract Surface acoustic waves (SAWs) have shown great potential for developing sensors for structural health monitoring (SHM) and lab‐on‐a‐chip (LOC) applications. Existing SAW sensors mainly rely on measuring the frequency shifts of high‐frequency (e.g., >0.1 GHz) resonance peaks. This study presents frequency‐locked wireless multifunctional SAW sensors that enable multiple wireless sensing functions, including strain sensing, temperature measurement, water presence detection, and vibration sensing. These sensors leverage SAW resonators on piezoelectric chips, inductive coupling‐based wireless power transmission, and, particularly, a frequency‐locked wireless sensing mechanism that works at low frequencies (e.g., <0.1 GHz). This mechanism locks the input frequency on the slope of a sensor's reflection spectrum and monitors the reflection signal's amplitude change induced by the changes of sensing parameters. The proof‐of‐concept experiments show that these wireless sensors can operate in a low‐power active mode for on‐demand wireless strain measurement, temperature sensing, and water presence detection. Moreover, these sensors can operate in a power‐free passive mode for vibration sensing, with results that agree well with laser vibrometer measurements. It is anticipated that the designs and mechanisms of the frequency‐locked wireless SAW sensors will inspire researchers to develop future wireless multifunctional sensors for SHM and LOC applications.